Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682595 | 0.86 | OPRD1 (0.45) | OPRD1KCNH2PRCPADRA2ASIGMAR1 | |
| SCHEMBL11684159 | 0.83 | SIGMAR1 (0.44) | OPRD1KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11683068 | 0.83 | ALDH1A1 (0.40) | OPRD1KCNH2KDM4EPRCPCA1 | |
| SCHEMBL11852054 | 0.83 | PRCP (0.42) | OPRD1KCNH2PRCPCA1CA2 | |
| SCHEMBL11781081 | 0.83 | PRCP (0.42) | OPRD1KCNH2KDM4EKMT2APRCP | |
| SCHEMBL11684960 | 0.81 | OPRD1 (0.57) | OPRD1KCNH2PRCPADRA2ASIGMAR1 | |
| SCHEMBL11684464 | 0.80 | PRCP (0.39) | PRCPCA1CA2CA9CA14 | |
| SCHEMBL11860134 | 0.78 | PRCP (0.52) | OPRD1PRCPADRA2ASIGMAR1 | |
| SCHEMBL11682880 | 0.76 | OPRD1 (0.41) | OPRD1KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11878975 | 0.76 | PRCP (0.39) | OPRD1KCNH2KMT2APRCPADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024263-A | ANALGESIC, ANTICONVULSANT, ANTIDEPRESSANT | AMERICAN HOECHST CORPORATION (US) | 1977-05-17 | — | — | US | claimed |
| US-4024263-A | ANALGESIC, ANTICONVULSANT, ANTIDEPRESSANT | AMERICAN HOECHST CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |