Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321849 | 0.77 | CES1 (0.52) | ALOX5ALDH1A1MAPK1L3MBTL1CES2 | |
| SCHEMBL2290221 | 0.76 | SMN1; SMN2 (0.51) | ALOX5ALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL11680944 | 0.76 | ALOX5 (0.49) | ALOX5NPC1RAB9ACES2CES1 | |
| SCHEMBL8458100 | 0.76 | NPC1 (0.51) | ALOX5ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL23258691 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1TSHRNPC1 | |
| SCHEMBL29291235 | 0.75 | ALOX5 (0.50) | ALOX5ALDH1A1MAPK1L3MBTL1NPC1 | |
| SCHEMBL9061013 | 0.74 | CES2 (0.48) | ALOX5ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL2233053 | 0.73 | ALDH1A1 (0.69) | ALDH1A1MAPK1TSHRNPC1RAB9A | |
| SCHEMBL203767 | 0.73 | TSHR (0.56) | ALDH1A1MAPK1L3MBTL1TSHRNPC1 | |
| SCHEMBL231282 | 0.73 | TSHR (0.61) | ALDH1A1MAPK1L3MBTL1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830869-A | METALLOPROTEASE INHIBITOR | PHARMACIA & UPJOHN COMPANY | 1998-11-03 | — | — | US | disclosed |