Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682900 | 0.91 | OPRD1 (0.48) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11683068 | 0.89 | ALDH1A1 (0.40) | TSHRRECQLSMN1; SMN2OPRD1KCNH2 | |
| SCHEMBL11684151 | 0.88 | OPRD1 (0.42) | OPRD1KCNH2PRCPSIGMAR1 | |
| SCHEMBL11682595 | 0.82 | OPRD1 (0.45) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11857141 | 0.81 | SIGMAR1 (0.50) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11852685 | 0.78 | PRCP (0.47) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11880970 | 0.77 | OPRD1 (0.44) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11879132 | 0.75 | OPRD1 (0.46) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11853705 | 0.75 | SIGMAR1 (0.49) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11862874 | 0.72 | OPRD1 (0.52) | OPRD1KCNH2PRCPALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024263-A | ANALGESIC, ANTICONVULSANT, ANTIDEPRESSANT | AMERICAN HOECHST CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |