Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PRCP | P42785 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684151 | 0.92 | OPRD1 (0.42) | OPRD1KCNH2PRCPSIGMAR1SLC18A3 | |
| SCHEMBL11686121 | 0.91 | TSHR (0.42) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11683068 | 0.85 | ALDH1A1 (0.40) | OPRD1KCNH2PRCP | |
| SCHEMBL11684960 | 0.79 | OPRD1 (0.57) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11862874 | 0.78 | OPRD1 (0.52) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11853407 | 0.77 | SIGMAR1 (0.56) | OPRD1KCNH2SIGMAR1 | |
| SCHEMBL11860423 | 0.76 | SIGMAR1 (0.54) | OPRD1KCNH2SIGMAR1ADRA2A | |
| SCHEMBL11682895 | 0.76 | KCNH2 (0.57) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11681373 | 0.76 | OPRD1 (0.60) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11681814 | 0.75 | OPRD1 (0.54) | OPRD1KCNH2PRCPSIGMAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024263-A | ANALGESIC, ANTICONVULSANT, ANTIDEPRESSANT | AMERICAN HOECHST CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |