SCHEMBL11684243

SCHEMBL11684243

O=[N+]([O-])c1ccc(Oc2cccc(F)n2)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSPB1 P04792 4/20 0.56
LMNA P02545 4/20 0.54
RAB9A P51151 3/20 0.54
HTT P42858 2/20 0.54
ALDH1A1 P00352 1/20 0.48
MAPT P10636 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
RXFP1 Q9HBX9 1/20 0.43
MAPK1 P28482 2/20 0.42
NPC1 O15118 1/20 0.42
MYOC Q99972 1/20 0.42
SRD5A2 P31213 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MCL1 Q07820 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8941507 0.78 MEN1 (0.50) HTTALDH1A1KDM4EMEN1KMT2A
SCHEMBL8941674 0.76 F2 (0.46) RAB9AHTTALDH1A1NPC1SMN1; SMN2
SCHEMBL8941703 0.75 MEN1 (0.46) MEN1KMT2A
SCHEMBL21330627 0.75 MEN1 (0.52) RAB9AHTTALDH1A1MEN1KMT2A
SCHEMBL21330612 0.75 MEN1 (0.51) HTTMEN1KMT2AL3MBTL1
SCHEMBL21330640 0.75 MEN1 (0.48) LMNARAB9AHTTALDH1A1MAPT
SCHEMBL11684536 0.75 MEN1 (0.47) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL3502988 0.74 LMNA (0.60) HSPB1LMNARAB9AHTTALDH1A1
SCHEMBL8563275 0.74 RAB9A (0.68) HSPB1LMNARAB9AHTTALDH1A1
SCHEMBL22061575 0.74 F2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4063928-A Composition and method of controlling undesired plant growth with substituted pyridinyloxy(thio)phenyl -acetamides, -ureas and urea derivatives THE DOW CHEMICAL COMPANY (US) 1977-12-20 US disclosed
US-4030910-A Substituted pyridinyloxy(thio)phenyl -acetamides, -ureas and urea derivatives, herbicidal compositions and methods containing same THE DOW CHEMICAL COMPANY (US) 1977-06-21 US disclosed
US-4003733-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1977-01-18 US disclosed
US-4003734-A Substituted pyridinyloxy(thio)phenyl-acetamides, -ureas and urea derivatives and herbicidal compositions and methods containing said compounds THE DOW CHEMICAL COMPANY (US) 1977-01-18 US disclosed
US-3931201-A HERBICIDE THE DOW CHEMICAL COMPANY (US) 1976-01-06 US disclosed