SCHEMBL11684270

SCHEMBL11684270

CCN(Cc1ccccc1)C(C)Oc1cccc(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.42
ALDH1A1 P00352 3/20 0.40
TSHR P16473 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
SLC22A2 O15244 1/20 0.40
SLC22A1 O15245 1/20 0.40
SLC22A3 O75751 1/20 0.40
ESR1 P03372 1/20 0.40
CHRM2 P08172 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
CHRM1 P11229 1/20 0.40
DRD2 P14416 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11682488 0.87 SIGMAR1 (0.40) BCHEALDH1A1TSHRSMN1; SMN2LMNA
SCHEMBL11682289 0.87 BCHE (0.49) BCHEALDH1A1TSHRSMN1; SMN2LMNA
SCHEMBL11681694 0.83 ADRA2B (0.45) ALDH1A1SMN1; SMN2LMNAHTTNPC1
SCHEMBL11682713 0.82 RECQL (0.41) ALDH1A1LMNAHTTOPRM1MAPT
SCHEMBL11683619 0.79 RAB9A (0.50) TSHRSMN1; SMN2LMNAHTTNPC1
SCHEMBL11681934 0.79 PTGES (0.40) BCHEALDH1A1TSHRSMN1; SMN2NPC1
SCHEMBL11676457 0.78 MAPT (0.41) SMN1; SMN2LMNADRD2MAPTTHRB
SCHEMBL9706148 0.77 KDM4E (0.39) BCHEALDH1A1TSHRSMN1; SMN2ADRA2A
SCHEMBL10429856 0.75 ADRA2A (0.43) BCHESMN1; SMN2LMNAHTTADRA2A
SCHEMBL11681961 0.75 CNR2 (0.40) BCHELMNACYP2D6PTGESCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4041024-A FOR POLYAMIDES AND POLYURETHANES BAYER AKTIENGESELLSCHAFT (DT) 1977-08-09 US disclosed