Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1168830 | 0.83 | HSD17B13 (0.53) | CSNK1DALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL1169382 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HPGDRAB9ACNR2KDM4E | |
| SCHEMBL28000025 | 0.76 | HSD17B13 (0.55) | CSNK1DNTRK1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL12991853 | 0.74 | BDKRB1 (0.57) | ALDH1A1HPGDRAB9ABDKRB1CNR2 | |
| SCHEMBL30382576 | 0.74 | NAMPT (0.50) | CSNK1DNTRK1HDAC3HDAC1HDAC2 | |
| SCHEMBL22560798 | 0.74 | CNR2 (0.53) | ALDH1A1HPGDRAB9ABDKRB1CNR2 | |
| SCHEMBL1169901 | 0.73 | RECQL (0.54) | ALDH1A1HPGDRAB9ACNR2P2RX7 | |
| SCHEMBL4520630 | 0.73 | LMNA (0.57) | ALDH1A1HPGDRAB9ABDKRB1CNR2 | |
| SCHEMBL13329834 | 0.73 | VNN1 (0.49) | CSNK1DNTRK1HDAC3HDAC1HDAC2 | |
| SCHEMBL30468285 | 0.72 | MAPK8 (0.57) | ALDH1A1HPGDKDM4EMAPK8HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987455-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2015-03-24 | — | — | US | disclosed |
| US-8557840-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2013-10-15 | — | — | US | disclosed |
| US-20110034334-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-10 | — | — | US | disclosed |
| EP-2254417-A2 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009090401-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034334-A1 | HERBICIDAL COMPOUNDS | CYP4Z1, CYP4F3, DDT | CSNK1D 2345/4885NTRK1 2222/4885ALDH1A1 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.