Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 3/20 | 0.52 |
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11702018 | 0.88 | CYP1A2 (0.58) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL10957418 | 0.88 | CYP1A2 (0.58) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL10453892 | 0.86 | CAPN1 (0.61) | CTSKCAPN1CASP1 | |
| SCHEMBL9656020 | 0.85 | CAPN1 (0.62) | CTSKCAPN1CASP1CTSLCTSB | |
| SCHEMBL11697381 | 0.84 | CASP1 (0.56) | CTSKCAPN1CASP1CTSSCTSL | |
| SCHEMBL10868042 | 0.83 | CAPN1 (0.58) | CTSKCAPN1CASP1 | |
| SCHEMBL9136357 | 0.82 | CTSK (0.62) | CTSKCTSSCTSLCTSB | |
| SCHEMBL29052552 | 0.81 | CTSK (0.77) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL29052549 | 0.81 | CTSK (0.77) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL10802560 | 0.81 | CTSL (0.73) | CTSKCAPN1CAPN2CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012367-A | Anti-ulcer polypeptides containing L-aspartic acid and intermediates thereto | G. D. SEARLE & CO. (US) | 1977-03-15 | — | — | US | disclosed |