Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL6269085 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL16265933 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL4370443 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28398822 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL66249 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28478211 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2590832 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL10566608 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL708617 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL10896609 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 827 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120484506-B | High-low temperature resistant, acid-alkali resistant and radiation resistant wave-transparent polyphenylene sulfide composite material and preparation method thereof | 广东鸿塑科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122051264-A | Reversible oxygen ion conductor ceramic fuel cell and preparation method thereof | 中国科学院上海应用物理研究所 | 2026-05-15 | — | — | CN | claimed |
| CN-122010188-A | Synthesis process of small-particle-size basic cobalt carbonate | 怀化炯诚新材料科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-4630187-A1 | PRODUCTION OF SILVER NANOPARTICLES BY GREEN SYNTHESIS USING HAZELNUT HUSK EXTRACT | Bahçesehir Üniversitesi (TR) | 2025-10-15 | — | — | EP | claimed |
| US-20250312777-A1 | CUBIC FLUORITE RARE-EARTH HIGH ENTROPY OXIDES AND THEIR CATALYSIS APPLICATIONS | UNIV KHALIFA SCIENCE & TECHNOLOGY (AE) | 2025-10-09 | — | — | US | claimed |
| CN-120078523-A | Medical rare earth glove for preventing sharps injury and preparation method | 天津市肿瘤医院（天津医科大学肿瘤医院） | 2025-06-03 | — | — | CN | claimed |
| CN-120091551-A | Flexible electromagnetic shielding material and preparation method thereof | 深圳鼎信德新材料科创有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-120044077-A | Sensitive material for detecting gastric cancer interference gas acetone, sensor and preparation method | 西安电子科技大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119976931-A | Synthesis method of high-purity anhydrous rare earth fluoride | 中国科学院上海有机化学研究所 | 2025-05-13 | — | — | CN | claimed |
| CN-119900109-A | Stannate fiber with high-entropy rare earth pyrochlore structure and preparation method thereof | 石家庄铁道大学 | 2025-04-29 | — | — | CN | claimed |
| CN-103495185-A | Preparation method of functionalized polyethyleneimine-modified multi-wall carbon nano-tube magnetic resonance imaging contrast agent | UNIV DONGHUA | 2014-01-08 | — | — | CN | claimed |
| US-20130230659-A1 | FINE-POROSITY CERAMIC COATING VIA SPPS | SIEMENS AKTIENGESELLSCHAFT (DE) | 2013-09-05 | — | — | US | claimed |
| EP-2614173-A1 | FINE-POROSITY CERAMIC COATING VIA SPPS | Siemens Aktiengesellschaft (DE) | 2013-07-17 | — | — | EP | claimed |
| CN-103012450-A | Gadolinium compound with dual functions of magnetic refrigeration function and ferroelectric function and preparation method thereof | UNIV NANKAI | 2013-04-03 | — | — | CN | claimed |
| WO-2012062547-A1 | FINE-POROSITY CERAMIC COATING VIA SPPS | SIEMENS AKTIENGESELLSCHAFT (DE) | 2012-05-18 | — | — | WO | claimed |
| EP-2453036-A1 | Fine porous ceramic coating using SPPS | SIEMENS AKTIENGESELLSCHAFT (DE) | 2012-05-16 | — | — | EP | claimed |
| EP-1993568-A2 | METHOD OF TREATING PERIODONTITIS AND OF REDUCING DENTINAL SENSITIVITY | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-11-26 | — | — | EP | claimed |
| WO-2007142804-A2 | PREPARATION OF COMPLEXING AGENTS AND METAL ION COMPLEXES IN AQUEOUS MEDIA | MALLINCKRODT INC. (US) | 2007-12-13 | — | — | WO | claimed |
| WO-2007100541-A2 | METHOD OF TREATING PERIODONTITIS AND OF REDUCING DENTINAL SENSITIVITY | RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 2007-09-07 | — | — | WO | claimed |
| US-20070196288-A1 | Method of treating periodontitis and of reducing dentinal sensitivity | RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK | 2007-08-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250312777-A1 | CUBIC FLUORITE RARE-EARTH HIGH ENTROPY OXIDES AND THEIR CATALYSIS APPLICATIONS | CA13, CA12, CA14 | MEN1 1161/4885KMT2A 3185/4885CA5A 845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.