Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL6269085 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL16265933 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL1170445 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28398822 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL66249 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28478211 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2590832 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL10566608 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL708617 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL10896609 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775963-A | Preparation method and application of metal ion doped ultra-small cerium oxide polishing abrasive | 复旦大学 | 2025-04-08 | — | — | CN | claimed |
| CN-119263356-A | Spherical (LPSGY) FO high-entropy nano material and preparation method and application thereof | 渤海大学 | 2025-01-07 | — | — | CN | claimed |
| CN-118908265-A | Gadolinium oxide doped cerium oxide nanocomposite and preparation method thereof and solid oxide fuel cell | 中国科学院赣江创新研究院 | 2024-11-08 | — | — | CN | claimed |
| CN-118439867-A | Method for preparing gadolinium hafnate solidified body by gel-casting process | 南华大学 | 2024-08-06 | — | — | CN | claimed |
| CN-118407137-A | Gadolinium hafnate ceramic whisker and preparation method thereof | 南华大学 | 2024-07-30 | — | — | CN | claimed |
| CN-118387921-A | Method for preparing nano gadolinium hafnate powder by ultrasonic spray pyrolysis | 南华大学 | 2024-07-26 | — | — | CN | claimed |
| CN-115779148-B | Dental implant surface coating and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2024-02-23 | — | — | CN | claimed |
| CN-117012950-A | Rare earth element modification method of lithium nickel manganese oxide anode and wide-temperature-zone application | 中国科学院金属研究所 | 2023-11-07 | — | — | CN | claimed |
| US-20230100234-A1 | PREPARATION OF PARAMAGNETIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2023-03-30 | — | — | US | claimed |
| CN-115779148-A | Surface coating of dental implant and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2023-03-14 | — | — | CN | claimed |
| CN-112812229-B | fluorescence/MRI dual-mode probe and preparation method and application thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2022-03-04 | — | — | CN | claimed |
| CN-113800604-A | Graphene-rare earth gadolinium co-doped Ti/SnO2-Sb composite electrode and preparation method thereof | 常州大学 | 2021-12-17 | — | — | CN | claimed |
| CN-112812229-A | fluorescence/MRI dual-mode probe and preparation method and application thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2021-05-18 | — | — | CN | claimed |
| CN-112320833-A | High temperature resistant SiO2-Gd2O3Composite aerogel and preparation method thereof | 湖南荣岚智能科技有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-110240903-B | Preparation method of small-size red-light fluorescent powder | 北京化工大学 | 2020-09-22 | — | — | CN | claimed |
| CN-110240903-A | A kind of preparation method of small size red light fluorescent powder | 北京化工大学 | 2019-09-17 | — | — | CN | claimed |
| CN-102151563-A | Gadolinium-yttrium-antimony based composite magnetic particle photo catalyst of core-shell structure, preparation and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2011-08-17 | — | — | CN | claimed |
| CN-102151572-A | Iron-gadolinium-antimony based composite magnetic particle photo-catalyst in core-shell structure as well as preparation and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2011-08-17 | — | — | CN | claimed |
| CN-102139210-A | Gadolinium-ytterbium-stibium based composite magnetic particle photocatalyst with core-shell structure, preparation and application | NANJING UNIVERSITY OF TECHNOLOGY | 2011-08-03 | — | — | CN | claimed |
| CN-102139209-A | Core-shell gadolinium indium antimony base composite magnetic-particle photochemical catalyst as well as preparation and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2011-08-03 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230100234-A1 | PREPARATION OF PARAMAGNETIC COMPOUNDS | MAG, PML, PYM1 | MEN1 326/4885KMT2A 2821/4885CA5A 2276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.