Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11713349 | 0.96 | LSS (0.46) | ESR1ESR2ABCB1MCHR1BCHE | |
| SCHEMBL11722280 | 0.94 | ESR1 (0.53) | ESR1ESR2ABCB1MCHR1NPC1 | |
| SCHEMBL11716196 | 0.89 | ESR1 (0.44) | ESR1ABCB1MCHR1HRH3L3MBTL1 | |
| SCHEMBL11718537 | 0.86 | LMNA (0.44) | ESR1SMN1; SMN2HRH3L3MBTL1 | |
| SCHEMBL11715619 | 0.86 | ALDH1A1 (0.51) | NPC1USP2RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL11717604 | 0.84 | BCHE (0.59) | BCHEACHEHRH3 | |
| SCHEMBL11713798 | 0.83 | MCHR1 (0.45) | ESR1ESR2MCHR1L3MBTL1 | |
| SCHEMBL11712203 | 0.82 | THRA (0.55) | BCHEACHE | |
| SCHEMBL11718751 | 0.82 | BCHE (0.52) | BCHEACHE | |
| SCHEMBL11719155 | 0.82 | KDM4E (0.52) | SMN1; SMN2BCHEACHELSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010272-A | ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |