Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719736 | 0.93 | KDM4E (0.38) | ELANELMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL11716939 | 0.88 | GSK3B (0.36) | ELANETSHRHSD17B10ALDH1A1NPSR1 | |
| SCHEMBL11718132 | 0.86 | LMNA (0.41) | ELANELMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL11712722 | 0.85 | LMNA (0.41) | ELANELMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL11716329 | 0.85 | LMNA (0.43) | ELANELMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL11720201 | 0.81 | LMNA (0.38) | ELANELMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL11712229 | 0.81 | MAOA (0.41) | TSHRHSD17B10ALDH1A1NPSR1KDM4E | |
| SCHEMBL11715783 | 0.81 | KDM4E (0.37) | ELANELMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL11716760 | 0.79 | GSK3B (0.40) | USP2 | |
| SCHEMBL11711439 | 0.79 | KDM4E (0.39) | ELANELMNAALDH1A1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |