Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 2/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.38 |
| ▸ | STK10 | O94804 | 1/20 | 0.38 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716939 | 0.88 | GSK3B (0.36) | GSK3BCDK4CCND1KDR | |
| SCHEMBL11712851 | 0.84 | KDR (0.41) | GSK3BROCK2CDK4CCND1CCNE2 | |
| SCHEMBL11716433 | 0.79 | ELANE (0.40) | USP2 | |
| SCHEMBL11719736 | 0.79 | KDM4E (0.38) | GSK3BCDK4CCND1USP2 | |
| SCHEMBL11712259 | 0.78 | PTGER4 (0.38) | GSK3BCDK4CCND1CHEK1WEE1 | |
| SCHEMBL11714114 | 0.78 | GSK3B (0.34) | GSK3BCDK4CCND1KDR | |
| SCHEMBL11718172 | 0.76 | CDK4 (0.36) | GSK3BCDK4CCND1CAMK2BCAMK2G | |
| SCHEMBL11715694 | 0.76 | CDK4 (0.37) | GSK3BPRKCBCDK4CCND1USP2 | |
| SCHEMBL11718359 | 0.76 | EGFR (0.41) | GSK3BROCK2CDK4CCND1CCNE2 | |
| SCHEMBL11718192 | 0.75 | MAPT (0.41) | GSK3BPRKCBCDK4CCND1CAMK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |