Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11712229 | 0.87 | MAOA (0.41) | MAPTPOLBNPSR1ALDH1A1KDM4E | |
| SCHEMBL11720540 | 0.84 | MAOA (0.50) | MAPTALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL11717398 | 0.81 | HPGD (0.41) | POLBTDP1NPSR1ALDH1A1KDM4E | |
| SCHEMBL11718359 | 0.81 | EGFR (0.41) | MAPTNPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL11717134 | 0.77 | KDM4E (0.43) | MAPTALDH1A1KDM4ESMN1; SMN2GSK3A | |
| SCHEMBL11716760 | 0.75 | GSK3B (0.40) | GSK3BPRKCBCDK4CCND1CAMK2B | |
| SCHEMBL11716003 | 0.74 | PTGER4 (0.39) | MAPTGSK3AGSK3BGAACDK4 | |
| SCHEMBL11717630 | 0.74 | GSK3B (0.38) | MAPTALDH1A1GSK3AGSK3BPRKCB | |
| SCHEMBL11716939 | 0.73 | GSK3B (0.36) | MAPTNPSR1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30463384 | 0.73 | ALDH1A1 (0.55) | MAPTTDP1NPSR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |