Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.78 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.65 |
| ▸ | CCR1 | P32246 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11797593 | 0.93 | OPRL1 (0.72) | OPRL1OPRM1CCR1SIGMAR1OPRD1 | |
| SCHEMBL11790501 | 0.84 | DRD2 (0.78) | OPRL1OPRM1CCR1SIGMAR1OPRD1 | |
| SCHEMBL8188731 | 0.82 | KCNA3 (0.58) | OPRL1 | |
| SCHEMBL8187774 | 0.81 | ADRA1D (0.58) | OPRL1OPRM1OPRD1 | |
| SCHEMBL8216361 | 0.80 | KCNA3 (0.56) | OPRL1 | |
| SCHEMBL2722580 | 0.79 | HTR1A (0.63) | GRIN2BSIGMAR1 | |
| SCHEMBL7547846 | 0.78 | HTR1A (0.61) | — | |
| SCHEMBL28753859 | 0.78 | HTR1A (0.61) | — | |
| SCHEMBL9710602 | 0.78 | ALDH1A1 (0.72) | OPRL1OPRM1GRIN2BLMNA | |
| SCHEMBL10836115 | 0.78 | KCNH2 (0.66) | OPRL1OPRM1GRIN2BOPRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032531-A | PIPERIDINE DERIVATIVES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1977-06-28 | — | — | US | disclosed |