Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297712 | 0.75 | ALDH1A1 (0.47) | TK1 | |
| SCHEMBL14577794 | 0.74 | TK1 (0.59) | TK1 | |
| SCHEMBL1144933 | 0.74 | TK1 (0.59) | TK1 | |
| SCHEMBL10105030 | 0.71 | CRBN (0.39) | TK1 | |
| SCHEMBL21345248 | 0.71 | TK1 (0.46) | TK1 | |
| SCHEMBL5614184 | 0.70 | TK1 (0.51) | TK1 | |
| SCHEMBL23622110 | 0.69 | TK1 (0.47) | TK1 | |
| SCHEMBL113251 | 0.68 | TK1 (0.68) | TK1 | |
| SCHEMBL5982831 | 0.68 | TK1 (0.68) | TK1 | |
| SCHEMBL3600197 | 0.68 | PRKCG (0.36) | TK1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016267-A | BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1977-04-05 | — | — | US | disclosed |