Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | FOS | P01100 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718537 | 0.97 | LMNA (0.44) | ESR1LMNAMAPK1L3MBTL1THRA | |
| SCHEMBL11713798 | 0.94 | MCHR1 (0.45) | ESR1LMNAMAPK1L3MBTL1KMT2A | |
| SCHEMBL11720107 | 0.89 | ESR1 (0.46) | ESR1L3MBTL1ABCB1MCHR1HRH3 | |
| SCHEMBL11720078 | 0.87 | ESR1 (0.55) | ESR1LMNAMAPK1L3MBTL1THRA | |
| SCHEMBL11713349 | 0.86 | LSS (0.46) | ESR1L3MBTL1ABCB1MCHR1 | |
| SCHEMBL11720978 | 0.85 | ESR1 (0.58) | ESR1LMNAMAPK1L3MBTL1KMT2A | |
| SCHEMBL11716788 | 0.84 | ESR1 (0.48) | ESR1LMNAMAPK1L3MBTL1THRA | |
| SCHEMBL11717138 | 0.84 | THRA (0.49) | ESR1LMNAMAPK1L3MBTL1THRA | |
| SCHEMBL11720909 | 0.83 | ALDH1A1 (0.54) | ESR1LMNAMAPK1L3MBTL1THRA | |
| SCHEMBL11722280 | 0.83 | ESR1 (0.53) | ESR1LMNAMAPK1L3MBTL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010272-A | ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |