Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716196 | 0.94 | ESR1 (0.44) | MCHR1ESR1STSLMNAMAPK1 | |
| SCHEMBL11718537 | 0.93 | LMNA (0.44) | ESR1LMNAMAPK1L3MBTL1KMT2A | |
| SCHEMBL11722280 | 0.89 | ESR1 (0.53) | MCHR1ESR1ESR2LMNAMAPK1 | |
| SCHEMBL11714292 | 0.86 | ESR1 (0.54) | ESR1STSLMNAMAPK1L3MBTL1 | |
| SCHEMBL11714087 | 0.84 | ESR1 (0.57) | ESR1LMNAMAPK1L3MBTL1KMT2A | |
| SCHEMBL11712256 | 0.83 | KMT2A (0.48) | ESR1LMNAMAPK1L3MBTL1KMT2A | |
| SCHEMBL11720078 | 0.83 | ESR1 (0.55) | ESR1LMNAMAPK1L3MBTL1CHRNB2 | |
| SCHEMBL11720107 | 0.83 | ESR1 (0.46) | MCHR1ESR1ESR2L3MBTL1 | |
| SCHEMBL11807252 | 0.82 | CHRNB2 (0.51) | MCHR1ESR1ESR2CHRNB2CHRNA4 | |
| SCHEMBL11720909 | 0.82 | ALDH1A1 (0.54) | ESR1LMNAMAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010272-A | ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |