Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730097 | 0.90 | TBXA2R (0.51) | ALDH1A1ADRB2KMT2AL3MBTL1TBXA2R | |
| SCHEMBL11735554 | 0.90 | PTGFR (0.45) | ADRB2TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11729918 | 0.90 | LMNA (0.44) | TBXAS1ALDH1A1PKMKMT2ATBXA2R | |
| SCHEMBL11852592 | 0.88 | ALDH1A1 (0.42) | TBXAS1ALDH1A1ADRB2GAAPKM | |
| SCHEMBL11728921 | 0.84 | ADRB2 (0.46) | ALDH1A1ADRB2KMT2ATBXA2RPTGER1 | |
| SCHEMBL11735701 | 0.84 | ADRB2 (0.41) | ALDH1A1ADRB2L3MBTL1PPARGPPARA | |
| SCHEMBL11850224 | 0.83 | PTGFR (0.57) | TBXAS1ALDH1A1GAAPKMKMT2A | |
| SCHEMBL11849657 | 0.82 | TBXA2R (0.44) | ALDH1A1ADRB2GAAPKMKMT2A | |
| SCHEMBL11726066 | 0.82 | PTGFR (0.44) | ALDH1A1ADRB2GAAL3MBTL1TBXA2R | |
| SCHEMBL11728191 | 0.82 | MEN1 (0.44) | ALDH1A1GAAKMT2ATBXA2RPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | claimed |
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |