Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.38 |
| ▸ | PTGIR | P43119 | 2/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11729925 | 0.86 | LTA4H (0.43) | KDM4ESMN1; SMN2LTA4HTBXA2RPLA2G4B | |
| SCHEMBL11725963 | 0.80 | ADRB2 (0.40) | KDM4ESMN1; SMN2LTA4H | |
| SCHEMBL11655973 | 0.80 | PLA2G4B (0.40) | KDM4ESMN1; SMN2LTA4HPTGIRPLA2G4B | |
| SCHEMBL11726052 | 0.79 | FAAH (0.40) | SMN1; SMN2LTA4H | |
| SCHEMBL11728048 | 0.78 | TBXA2R (0.40) | KDM4ESMN1; SMN2TBXA2RPLA2G4B | |
| SCHEMBL11731610 | 0.78 | KDM4E (0.41) | KDM4ESMN1; SMN2LTA4H | |
| SCHEMBL11727616 | 0.77 | LTA4H (0.39) | KDM4ESMN1; SMN2LTA4HTBXA2RPLA2G4B | |
| SCHEMBL11728906 | 0.77 | LTA4H (0.39) | KDM4ESMN1; SMN2LTA4HTBXA2RPLA2G4B | |
| SCHEMBL11728916 | 0.77 | LTA4H (0.39) | KDM4ESMN1; SMN2LTA4HTBXA2RPLA2G4B | |
| SCHEMBL11725299 | 0.77 | PTGFR (0.43) | TBXA2RPLA2G4BPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |