Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 5/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11729918 | 0.87 | LMNA (0.44) | TBXA2RMEN1KMT2ALMNAPLA2G4B | |
| SCHEMBL11735701 | 0.81 | ADRB2 (0.41) | ADRB2ADRB1ADRB3CA12CA2 | |
| SCHEMBL11726046 | 0.79 | FAAH (0.40) | — | |
| SCHEMBL11655973 | 0.79 | PLA2G4B (0.40) | ADRB2ADRB1CYP1A2ADRB3LMNA | |
| SCHEMBL11728055 | 0.78 | KDM4E (0.45) | TBXA2RPLA2G4BKDM4ESMN1; SMN2 | |
| SCHEMBL11730097 | 0.77 | TBXA2R (0.51) | TBXA2RADRB2ADRB1CYP1A2ADRB3 | |
| SCHEMBL11727609 | 0.77 | LTA4H (0.38) | TBXA2RADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL11725291 | 0.77 | TBXAS1 (0.43) | TBXA2RADRB2KMT2A | |
| SCHEMBL11603926 | 0.77 | EPHX2 (0.46) | CYP1A2 | |
| SCHEMBL11733725 | 0.74 | TBXA2R (0.39) | TBXA2RADRB1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |