Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 5/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PKLR | P30613 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728371 | 0.90 | LMNA (0.44) | PTGFRPTGER1ALDH1A1TBXA2RPTGER2 | |
| SCHEMBL11728838 | 0.87 | ALDH1A1 (0.42) | PTGFRPTGER1ALDH1A1 | |
| SCHEMBL11730097 | 0.80 | TBXA2R (0.51) | PTGFRPTGER1ALDH1A1TBXA2RPTGER2 | |
| SCHEMBL11729890 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TBXA2RLMNATHRBL3MBTL1 | |
| Water SCHEMBL11728791 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TBXA2RLMNATHRBL3MBTL1 | |
| SCHEMBL11734582 | 0.77 | FFAR4 (0.46) | ALDH1A1FABP4 | |
| SCHEMBL11728423 | 0.77 | FAAH (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL11601260 | 0.76 | FFAR4 (0.65) | PTGFRALDH1A1TBXA2RPTGER2FABP4 | |
| SCHEMBL11602007 | 0.76 | FFAR4 (0.65) | PTGFRALDH1A1TBXA2RPTGER2FABP4 | |
| SCHEMBL11733330 | 0.76 | CYP1A2 (0.47) | PTGFRPTGER1ALDH1A1TBXA2RPTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |