Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | PTGFR | P43088 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11729975 | 0.89 | RAB9A (0.44) | CYP1A2TDP1TBXA2RALDH1A1HPGD | |
| SCHEMBL11731240 | 0.88 | ALDH1A1 (0.43) | GAATBXA2RALDH1A1FABP4KMT2A | |
| SCHEMBL11726347 | 0.88 | CYP1A2 (0.41) | CYP1A2GAACYP2C19TDP1ALDH1A1 | |
| SCHEMBL11730097 | 0.86 | TBXA2R (0.51) | CYP1A2TBXA2RALDH1A1FABP4MEN1 | |
| SCHEMBL11725298 | 0.86 | CYP1A2 (0.45) | CYP1A2GAACYP2C19TDP1TBXA2R | |
| SCHEMBL11733725 | 0.84 | TBXA2R (0.39) | TBXA2RALDH1A1FABP4KMT2ALMNA | |
| SCHEMBL11850224 | 0.83 | PTGFR (0.57) | GAATBXA2RALDH1A1FABP4KMT2A | |
| Water SCHEMBL11730250 | 0.82 | PTGFR (0.56) | GAATBXA2RALDH1A1FABP4KMT2A | |
| SCHEMBL11729918 | 0.82 | LMNA (0.44) | TBXA2RALDH1A1FABP4MEN1KMT2A | |
| SCHEMBL11729890 | 0.81 | ALDH1A1 (0.45) | TBXA2RALDH1A1HTTLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |