Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920193 | 0.83 | BRD4 (0.45) | PDK1ACKR3MIFWNT1GSK3B | |
| SCHEMBL28639087 | 0.82 | LMNA (0.42) | TSHRLMNAPOLBALDH1A1PDK1 | |
| SCHEMBL19437299 | 0.81 | PDK1 (0.45) | TSHRLMNAPOLBALDH1A1PDK1 | |
| SCHEMBL11731563 | 0.81 | RAB9A (0.36) | TSHRLMNAPOLBALDH1A1RAB9A | |
| SCHEMBL25075052 | 0.80 | ALDH1A1 (0.37) | TSHRLMNAALDH1A1PDK1ACKR3 | |
| SCHEMBL13887587 | 0.80 | WNT1 (0.38) | TSHRPDK1ACKR3WNT1GSK3B | |
| SCHEMBL23276967 | 0.80 | CYP1A2 (0.41) | TSHRPDK1ACKR3WNT1GSK3B | |
| SCHEMBL4550200 | 0.80 | CYP1A2 (0.41) | TSHRPDK1ACKR3WNT1GSK3B | |
| SCHEMBL16770006 | 0.79 | PDK1 (0.46) | LMNAPOLBALDH1A1PDK1ACKR3 | |
| SCHEMBL28474394 | 0.79 | GAA (0.43) | TSHRLMNAPOLBALDH1A1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4062956-A | Substituted 2-(2-hydroxyethyl)tetrahydro-1,4 oxazines and quaternary salts thereof useful for treating spasmodic syndromes | CENTRE EUROPEEN DE RECHERCHES MAUVERNAY (FR) | 1977-12-13 | — | — | US | disclosed |