Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 18/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730097 | 0.89 | TBXA2R (0.51) | ADRB2ADRB1ADRB3TBXA2RPTGER1 | |
| SCHEMBL11731318 | 0.88 | TBXAS1 (0.41) | TBXAS1ADRB2ADRB1ADRB3 | |
| SCHEMBL11850224 | 0.83 | PTGFR (0.57) | TBXAS1TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11728034 | 0.83 | TBXA2R (0.47) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11726284 | 0.83 | TBXA2R (0.45) | ADRB2ADRB1ADRB3TBXA2RPTGER1 | |
| SCHEMBL11728921 | 0.83 | ADRB2 (0.46) | ADRB2ADRB1ADRB3TBXA2RPTGER1 | |
| Water SCHEMBL11730250 | 0.83 | PTGFR (0.56) | TBXAS1TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11735554 | 0.83 | PTGFR (0.45) | ADRB2TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11729918 | 0.82 | LMNA (0.44) | TBXAS1TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11725291 | 0.82 | TBXAS1 (0.43) | TBXAS1ADRB2TBXA2RPTGER1PTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |