Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | ACR | P10323 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2374902 | 0.83 | SERPINE1 (0.54) | SERPINE1TNFRSF1APTGS2ALOX5PTGS1 | |
| SCHEMBL8777982 | 0.80 | TSHR (0.58) | SERPINE1TNFRSF1APTGS2ALOX5PTGS1 | |
| SCHEMBL8777915 | 0.78 | TTR (0.55) | SERPINE1TNFRSF1APTGS2ALOX5PTGS1 | |
| SCHEMBL11786628 | 0.77 | SELL (0.52) | SERPINE1SLC6A3TNFRSF1APTGS2ALOX5 | |
| SCHEMBL9280957 | 0.77 | ALOX5 (0.55) | SERPINE1TNFRSF1APTGS2ALOX5PTGS1 | |
| SCHEMBL1796301 | 0.77 | PTGS1 (0.48) | SERPINE1TNFRSF1APTGS2ALOX5PTGS1 | |
| SCHEMBL29612711 | 0.77 | PTGS1 (0.48) | SERPINE1TNFRSF1APTGS2ALOX5PTGS1 | |
| SCHEMBL11741030 | 0.76 | VCAM1 (0.45) | PTGS2ALOX5PTGS1KMT2ALMNA | |
| SCHEMBL11729947 | 0.76 | NSD2 (0.63) | SERPINE1TNFRSF1APTGS2ALOX5PTGS1 | |
| SCHEMBL11745553 | 0.75 | PTGS2 (0.38) | SERPINE1TNFRSF1APTGS2ALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038249-A | METAL SALTS OF BENZOYLOXYBENZOATES AND COMPOSITIONS STABILIZED THEREWITH | CIBA-GEIGY CORPORATION (US) | 1977-07-26 | — | — | US | disclosed |