Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 2/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029815 | 0.67 | MAPT (0.53) | KDM4EALDH1A1HPGDALOX12TPMT | |
| SCHEMBL10900703 | 0.65 | MAPK1 (0.40) | ALDH1A1CA2MAPK1 | |
| Butane SCHEMBL10399492 | 0.65 | POLB (0.53) | CHEK1KDM4EALDH1A1HPGDALOX12 | |
| SCHEMBL4597241 | 0.64 | TPMT (0.40) | CHEK1KDM4EALDH1A1HPGDALOX12 | |
| Butyl Chloride SCHEMBL10492137 | 0.64 | MEN1 (0.51) | CHEK1KDM4EALDH1A1HPGDALOX12 | |
| SCHEMBL8756369 | 0.64 | TDP2 (0.50) | TPMTTTRTDP2TP53 | |
| SCHEMBL1767975 | 0.63 | TGM2 (0.42) | CHEK1ALDH1A1TP53MDM2CA2 | |
| Hexanoate SCHEMBL11747038 | 0.63 | ALDH1A1 (0.51) | CHEK1KDM4EALDH1A1HPGDALOX12 | |
| SCHEMBL11290731 | 0.63 | GRM1 (0.52) | PLA2G2AMEN1KMT2ATP53 | |
| SCHEMBL28038807 | 0.63 | MAPK1 (0.38) | ALDH1A1MEN1KMT2ACA2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041065-A | WIRE COATINGS, FILMS, MOLDINGS | STANDARD OIL COMPANY (INDIANA) (US) | 1977-08-09 | — | — | US | disclosed |