Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | LIPE | Q05469 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751236 | 0.80 | KDM4E (0.40) | ALDH1A1KMT2A | |
| SCHEMBL11749092 | 0.73 | ALDH1A1 (0.42) | BCHEACHELIPEALDH1A1KMT2A | |
| SCHEMBL13106169 | 0.63 | HSD11B1 (0.41) | ALDH1A1XPO1 | |
| SCHEMBL11749281 | 0.63 | P2RX7 (0.38) | ALDH1A1SCN9ARORCPIK3CDPIK3R2 | |
| SCHEMBL11749925 | 0.63 | LMNA (0.42) | BCHEACHELIPEALDH1A1KMT2A | |
| SCHEMBL11755492 | 0.62 | TSHR (0.40) | ALDH1A1KMT2ASCN9ARORC | |
| SCHEMBL11750240 | 0.60 | BCHE (0.44) | BCHEACHELIPEGRIN2BALDH1A1 | |
| SCHEMBL11757415 | 0.60 | F2 (0.40) | ALDH1A1KMT2A | |
| SCHEMBL11748834 | 0.60 | KDM4E (0.46) | ALDH1A1KMT2A | |
| SCHEMBL11751025 | 0.60 | ALDH1A1 (0.50) | BCHEACHELIPEALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051252-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |