Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170360 | 0.79 | CA12 (0.42) | CA2MAPTALDH1A1POLBMAOA | |
| SCHEMBL6214043 | 0.77 | MAPT (0.43) | MAPTALDH1A1POLBHPGDMAOB | |
| SCHEMBL11752182 | 0.77 | GSTP1 (0.33) | CA2MAPTALDH1A1HPGDGSTP1 | |
| SCHEMBL12892333 | 0.76 | ALOX15 (0.55) | MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL515056 | 0.76 | MAOB (0.50) | CA2MAPTALDH1A1POLBHPGD | |
| SCHEMBL5510525 | 0.73 | PTGS2 (0.50) | MAPTALDH1A1POLBHPGDCYP2C9 | |
| SCHEMBL4408306 | 0.72 | ALDH1A1 (0.64) | CA2CA5AMAPTALDH1A1POLB | |
| SCHEMBL469848 | 0.70 | ALDH1A1 (0.52) | CA2CA5AMAPTALDH1A1POLB | |
| SCHEMBL2641227 | 0.70 | LTA4H (0.47) | ESR1CYP1A2CYP2C19LMNA | |
| SCHEMBL99544 | 0.70 | DAO (0.43) | CA2MAOBCA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060688-A | Cephalosporin intermediates | ELI LILLY AND COMPANY (US) | 1977-11-29 | — | — | US | disclosed |