Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170360 | 0.82 | CA12 (0.42) | GSTP1CA12CA1CA2CA4 | |
| SCHEMBL6214043 | 0.80 | MAPT (0.43) | ADAM17MAPTHPGDMEN1ALDH1A1 | |
| SCHEMBL11749270 | 0.77 | CA2 (0.42) | GSTP1CA12CA1CA2CA4 | |
| SCHEMBL98311 | 0.77 | ALDH1A1 (0.47) | MEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL514644 | 0.72 | L3MBTL1 (0.47) | MAPTHPGD | |
| SCHEMBL514661 | 0.72 | APP (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2641227 | 0.72 | LTA4H (0.47) | MEN1KMT2A | |
| SCHEMBL10947087 | 0.72 | NQO1 (0.64) | CA12CA1CA2CA7CA9 | |
| SCHEMBL99544 | 0.72 | DAO (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6978990 | 0.72 | TDP1 (0.52) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060688-A | Cephalosporin intermediates | ELI LILLY AND COMPANY (US) | 1977-11-29 | — | — | US | disclosed |