Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | MC3R | P41968 | 2/20 | 0.46 |
| ▸ | MC1R | Q01726 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18862951 | 0.86 | HSD11B1 (0.48) | HSD11B1MC4RMC3RMC1RABCB1 | |
| SCHEMBL18862950 | 0.86 | HSD11B1 (0.48) | HSD11B1MC4RMC3RMC1RABCB1 | |
| SCHEMBL5800629 | 0.83 | TACR1 (0.46) | HSD11B1MC4RMC3RMC1RABCB1 | |
| SCHEMBL27946634 | 0.82 | ABCB1 (0.62) | ABCB1TACR1 | |
| SCHEMBL16197157 | 0.80 | PSEN1 (0.56) | HSD11B1MC4RMC3RMC1RABCB1 | |
| SCHEMBL23459127 | 0.77 | SCD5 (0.57) | HSD11B1MC4RMC3RMC1RSCD5 | |
| SCHEMBL908981 | 0.77 | SCD5 (0.57) | HSD11B1MC4RMC3RMC1RSCD5 | |
| SCHEMBL28334140 | 0.76 | NR1H2 (0.56) | ABCB1DAGLA | |
| SCHEMBL28334137 | 0.76 | NR1H2 (0.56) | ABCB1DAGLA | |
| SCHEMBL4629395 | 0.75 | HSD11B1 (0.61) | HSD11B1SCD5GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4057414-A | O-(METHYLAMINOSULFONYL)-GLYCOLIC ACID HEXAMETHYLENE OR HEPTAMETHYLENE AMIDE, PROPIONIC ACID 3,4-DICHLOROANILIDE | BASF AKTIENGESELLSCHAFT (DT) | 1977-11-08 | — | — | US | disclosed |
| US-4030909-A | BENZOTHIADIAZINONE DIOXIDE AND A GLYCOLIC ACID AMIDE | BASF AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | disclosed |
| US-4001217-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |