SCHEMBL1176372

SCHEMBL1176372

C=CCN(C)C(=O)C(=C)C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8544050 0.80 ALDH1A1 (0.43) ALDH1A1
SCHEMBL21235963 0.80 ALDH1A1 (0.34) ALDH1A1
SCHEMBL15413189 0.79 ALDH1A1 (0.37) ALDH1A1
SCHEMBL131046 0.79 ALDH1A1 (0.46) ALDH1A1TDP1
SCHEMBL7783304 0.78 ALDH1A1 (0.33) ALDH1A1
SCHEMBL207433 0.78
SCHEMBL327516 0.77 ALDH1A1 (0.35) ALDH1A1TDP1
Ammonia Solution, Strong SCHEMBL28035861 0.77 ALDH1A1 (0.45) ALDH1A1TDP1
SCHEMBL23786831 0.76 ALDH1A1 (0.30) ALDH1A1
SCHEMBL278426 0.76 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132972-A1 PROCESS FOR PREPARING A DENTAL RESIN-MODIFIED GLASS IONOMER COMPOSITION DENTSPLY SIRONA INC. (US) 2023-05-04 US disclosed
US-20180214351-A1 DENTAL ADHESIVE DENTSPLY SIRONA INC. (US) 2018-08-02 US disclosed
US-20170296442-A1 AQUEOUS DENTAL GLASS IONOMER COMPOSITION DENTSPLY SIRONA INC. (US) 2017-10-19 US disclosed
US-20170296441-A1 AQUEOUS DENTAL GLASS IONOMER COMPOSITION DENTSPLY SIRONA INC. (US) 2017-10-19 US disclosed
US-9562327-B2 Process for the production of paper AKZO NOBEL N.V. (NL) 2017-02-07 US disclosed
CN-103391811-B Microcapsules using paraffin wax composition as capsule-core BASF SE (DE) 2016-05-18 CN disclosed
US-9139958-B2 Process for the production of paper AKZO NOBEL N.V. (NL) 2015-09-22 US disclosed
EP-1834040-B1 A PROCESS FOR THE PRODUCTION OF PAPER AKZO NOBEL NV (NL) 2015-02-18 EP disclosed
US-20140318727-A1 PROCESS FOR THE PRODUCTION OF PAPER AKZO NOBEL N.V. (NL) 2014-10-30 US disclosed
US-8790493-B2 Process for the production of paper AKZO NOBEL N.V. (NL) 2014-07-29 US disclosed
CN-100345930-C Use of aqueous microcapsule dispersions as heat transfer liquids BASF AG (DE) 2007-10-31 CN disclosed
CN-1993444-A Coarse-particle microcapsule preparation BASF AG (DE) 2007-07-04 CN disclosed
WO-2007073321-A1 SIZING OF PAPER AKZO NOBEL N.V. (NL) 2007-06-28 WO disclosed
US-20070137523-A1 Sizing of paper AKZO NOBEL N.V. (NL) 2007-06-21 US disclosed
WO-2006123989-A2 A PROCESS FOR THE PRODUCTION OF PAPER AKZO NOBEL N.V. (NL) 2006-11-23 WO disclosed
US-20060254464-A1 Process for the production of paper AKZO NOBEL N.V. (NL) 2006-11-16 US disclosed
US-20060130991-A1 Process for the production of paper AKZO NOBEL N.V. (NL) 2006-06-22 US disclosed
CN-1774489-A Use of aqueous microcapsule dispersions as heat transfer liquids BASF AG (DE) 2006-05-17 CN disclosed
EP-0838537-B1 METAL SURFACE TREATMENTS, METHOD FOR TREATING METAL SURFACE, AND SURFACE-TREATED METALLIC MATERIAL NIPPON PAINT CO LTD (JP) 2001-10-17 EP disclosed
EP-0838537-A1 METAL SURFACE TREATMENTS, METHOD FOR TREATING METAL SURFACE, AND SURFACE-TREATED METALLIC MATERIAL NIPPON PAINT CO., LTD. (JP) 1998-04-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170296441-A1 AQUEOUS DENTAL GLASS IONOMER COMPOSITION GLUL, GDA, PHAX ALDH1A1 1935/4885TDP1 1957/4885
US-20170296442-A1 AQUEOUS DENTAL GLASS IONOMER COMPOSITION COG1, GDA, COG2 ALDH1A1 2568/4885TDP1 2966/4885
US-20230132972-A1 PROCESS FOR PREPARING A DENTAL RESIN-MODIFIED GLASS IONOMER COMPOSITION PICALM, COG1, GYPA ALDH1A1 1756/4885TDP1 2194/4885
US-20180214351-A1 DENTAL ADHESIVE CDH1, ITGA5, ICAM1 ALDH1A1 404/4885TDP1 1425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.