Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | ULK1 | O75385 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757461 | 0.93 | CASP6 (0.60) | ENPP2CASP6CTDSP1ULK1NT5E | |
| SCHEMBL6559613 | 0.90 | CASP6 (0.65) | ENPP2CASP6CTDSP1ULK1NT5E | |
| SCHEMBL11582870 | 0.89 | CASP6 (0.64) | ENPP2CASP6CTDSP1ULK1NT5E | |
| SCHEMBL11441389 | 0.88 | ULK1 (0.52) | ENPP2CASP6CTDSP1ULK1NT5E | |
| SCHEMBL14640094 | 0.87 | NT5E (0.61) | ENPP2CASP6CTDSP1NT5EMEN1 | |
| SCHEMBL14601340 | 0.87 | TIMP3 (0.64) | ENPP2NT5EMEN1KMT2ATIMP3 | |
| SCHEMBL11760372 | 0.87 | TIMP3 (0.64) | ENPP2NT5EMEN1KMT2ATIMP3 | |
| SCHEMBL10326996 | 0.87 | ENPP2 (0.71) | ENPP2CASP6CTDSP1NT5EMEN1 | |
| SCHEMBL11760343 | 0.86 | TIMP3 (0.63) | ENPP2NT5EMEN1KMT2ATIMP3 | |
| SCHEMBL11764462 | 0.85 | SIRT1 (0.58) | ENPP2ULK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4027038-A | NAPHTHALENEDISULFONIC ACID UREIDES | AMERICAN CYANAMID COMPANY (US) | 1977-05-31 | — | — | US | disclosed |