Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778072 | 0.74 | CA1 (0.46) | MAPTKDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL11778823 | 0.70 | MAPT (0.58) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11783471 | 0.65 | MEN1 (0.53) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL11780958 | 0.63 | CA1 (0.55) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL21525769 | 0.62 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2TDP1POLB | |
| SCHEMBL11782600 | 0.62 | MEN1 (0.43) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL11782595 | 0.62 | MEN1 (0.43) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL11781708 | 0.62 | MEN1 (0.48) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL11799270 | 0.61 | CA1 (0.43) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11780330 | 0.61 | MEN1 (0.47) | MAPTLMNASMN1; SMN2POLBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |