Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11780536 | 0.93 | BDKRB1 (0.41) | MEN1KMT2AGAAGFERL3MBTL1 | |
| SCHEMBL11841803 | 0.91 | L3MBTL1 (0.50) | MEN1KMT2AL3MBTL1GPR55MAPT | |
| SCHEMBL11783802 | 0.89 | CISD1 (0.47) | MEN1KMT2AGAAL3MBTL1PTPN1 | |
| SCHEMBL11784962 | 0.88 | L3MBTL1 (0.46) | MEN1KMT2AL3MBTL1GPR55MAPT | |
| SCHEMBL11782595 | 0.84 | MEN1 (0.43) | MEN1KMT2AGAAGFERL3MBTL1 | |
| SCHEMBL11782600 | 0.84 | MEN1 (0.43) | MEN1KMT2AGAAGFERL3MBTL1 | |
| SCHEMBL11777201 | 0.81 | GAA (0.45) | MEN1KMT2AGAAL3MBTL1MAPT | |
| SCHEMBL11780992 | 0.80 | L3MBTL1 (0.41) | MEN1KMT2AL3MBTL1PTPN1GPR55 | |
| SCHEMBL11845448 | 0.80 | ALOX15 (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL11783471 | 0.79 | MEN1 (0.53) | MEN1KMT2AGAAGFERL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |