Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11781708 | 0.93 | MEN1 (0.48) | MEN1KMT2AGAAGFERL3MBTL1 | |
| SCHEMBL11777201 | 0.88 | GAA (0.45) | MEN1KMT2AGAAL3MBTL1NPC1 | |
| SCHEMBL11783802 | 0.86 | CISD1 (0.47) | MEN1KMT2AGAAL3MBTL1RAB9A | |
| SCHEMBL11841803 | 0.84 | L3MBTL1 (0.50) | MEN1KMT2AL3MBTL1LMNATSHR | |
| SCHEMBL11780330 | 0.83 | MEN1 (0.47) | BDKRB1MEN1KMT2AGAAGFER | |
| SCHEMBL11780992 | 0.82 | L3MBTL1 (0.41) | MEN1KMT2AL3MBTL1PTPN1SMN1; SMN2 | |
| SCHEMBL11784962 | 0.81 | L3MBTL1 (0.46) | MEN1KMT2AL3MBTL1LMNATSHR | |
| SCHEMBL11780616 | 0.80 | PKM (0.59) | BDKRB1MEN1KMT2AGAAGFER | |
| SCHEMBL11842089 | 0.80 | LMNA (0.51) | MEN1KMT2AL3MBTL1PKMLMNA | |
| SCHEMBL11782595 | 0.78 | MEN1 (0.43) | MEN1KMT2AGAAGFERL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |