Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554941 | 0.81 | SIGMAR1 (0.47) | CHRM2ADRA2BDRD3SIGMAR1HRH3 | |
| SCHEMBL11800787 | 0.80 | ABCC4 (0.35) | ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL11729199 | 0.78 | L3MBTL1 (0.61) | DRD3HRH3ALDH1A1HPGDMAOB | |
| SCHEMBL11751985 | 0.77 | KDM4E (0.67) | HRH3ALDH1A1HPGDMAOBMAPT | |
| SCHEMBL11794977 | 0.76 | L3MBTL1 (0.59) | DRD3ALDH1A1HPGDMAOBLMNA | |
| SCHEMBL11803305 | 0.76 | MAOB (0.64) | HRH3ALDH1A1HPGDMAOBLMNA | |
| SCHEMBL11798123 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HPGDMAOBMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL11748357 | 0.75 | MAOB (0.65) | HRH3ALDH1A1HPGDMAOBLMNA | |
| SCHEMBL19253135 | 0.74 | KDM4E (0.49) | ALDH1A1HPGDMAOBMAPTKDM4E | |
| SCHEMBL13818588 | 0.73 | CYP2D6 (0.54) | CHRM2ADRA2BDRD3SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |