Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TPMT | P51580 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800920 | 0.83 | PDK1 (0.51) | ALDH1A1KDM4EGAATPMTHPGD | |
| SCHEMBL985523 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL6343891 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL1191343 | 0.78 | TPMT (0.79) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL10777443 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL9222707 | 0.77 | TAS1R3 (0.52) | ALDH1A1KDM4ETAS1R3TAS1R1HPGD | |
| SCHEMBL2391150 | 0.76 | ALDH1A1 (0.65) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL11800419 | 0.75 | TTR (0.58) | ALDH1A1HPGDHSD17B10PDK1 | |
| SCHEMBL25184423 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL11799798 | 0.74 | PDK1 (0.56) | ALDH1A1TPMTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933472-A | Substituted alkylaryl ketones and methods of use as herbicides | BUCKMAN LABORATORIES, INC. (US) | 1976-01-20 | — | — | US | disclosed |