Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.56 |
| ▸ | DRD2 | P14416 | 7/20 | 0.56 |
| ▸ | HTR2A | P28223 | 6/20 | 0.56 |
| ▸ | HTR6 | P50406 | 6/20 | 0.56 |
| ▸ | HTR7 | P34969 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HEXA | P06865 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809762 | 0.86 | HTR1A (0.54) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11630376 | 0.86 | DRD2 (0.55) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11808504 | 0.85 | CCR3 (0.56) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11807499 | 0.85 | DRD2 (0.57) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11804225 | 0.85 | DRD2 (0.57) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11811290 | 0.84 | KDM4E (0.55) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11809981 | 0.81 | DRD2 (0.55) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11629569 | 0.80 | L3MBTL1 (0.44) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11814435 | 0.80 | HTR1A (0.57) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11628444 | 0.80 | RAD52 (0.58) | KDM4ERAD52MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935227-A | ANTIDEPRESSANTS, ANTIANXIETY, ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1976-01-27 | — | — | US | disclosed |