Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11634992 | 0.88 | L3MBTL1 (0.53) | L3MBTL1RAD52MEN1KMT2AKDM4E | |
| SCHEMBL11632571 | 0.88 | L3MBTL1 (0.43) | L3MBTL1RAD52MEN1KMT2AKDM4E | |
| SCHEMBL11634977 | 0.87 | L3MBTL1 (0.47) | L3MBTL1KDM4EMAPTRAB9ACCR1 | |
| SCHEMBL11636824 | 0.84 | L3MBTL1 (0.49) | L3MBTL1RAD52MEN1KMT2AKDM4E | |
| SCHEMBL11631631 | 0.83 | L3MBTL1 (0.46) | L3MBTL1RAD52MEN1KMT2AKDM4E | |
| SCHEMBL11633475 | 0.83 | L3MBTL1 (0.45) | L3MBTL1KDM4EMAPTRAB9ACCR1 | |
| SCHEMBL11629536 | 0.82 | SIGMAR1 (0.46) | L3MBTL1MEN1KMT2ACCR1DRD2 | |
| SCHEMBL11630996 | 0.81 | SIGMAR1 (0.46) | L3MBTL1MEN1KMT2ACCR1HTR1A | |
| SCHEMBL11629977 | 0.81 | SIGMAR1 (0.46) | L3MBTL1MEN1KMT2ACCR1HTR1A | |
| SCHEMBL11804698 | 0.80 | HTR1A (0.56) | RAD52MEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |