Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11811391 | 0.86 | ADORA3 (0.32) | AURKAKDRAURKB | |
| SCHEMBL11811404 | 0.83 | HSD11B1 (0.35) | DYRK1AAURKAKDRAURKB | |
| SCHEMBL11809102 | 0.82 | CSNK1E (0.36) | CSNK1ECLK1CLK2CLK3GSK3B | |
| SCHEMBL11861299 | 0.81 | ALDH1A1 (0.37) | ABL1 | |
| SCHEMBL11806507 | 0.80 | TDP1 (0.40) | CSNK1ECLK1CLK2CLK3CDK5 | |
| SCHEMBL11561320 | 0.76 | CSNK1E (0.34) | CSNK1ECLK1CLK2CLK3GSK3B | |
| SCHEMBL11811136 | 0.72 | BRD4 (0.36) | ABL1 | |
| SCHEMBL31698750 | 0.71 | CSNK1E (0.33) | CSNK1ECLK1CLK2CLK3GSK3B | |
| SCHEMBL11520254 | 0.71 | CSNK1E (0.38) | CSNK1ECLK1CLK2CLK3GSK3B | |
| SCHEMBL11812193 | 0.71 | MBOAT4 (0.32) | AURKAKDRAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | claimed |
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |