Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.36 |
| ▸ | CASR | P41180 | 3/20 | 0.35 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11811344 | 0.87 | DHFR (0.30) | ABL1 | |
| SCHEMBL11809102 | 0.84 | CSNK1E (0.36) | ABL1 | |
| SCHEMBL11859049 | 0.82 | CYP1A2 (0.37) | BRD4CASRABL1 | |
| SCHEMBL11804027 | 0.81 | DHFR (0.32) | — | |
| SCHEMBL11812652 | 0.76 | CHRNB2 (0.36) | — | |
| SCHEMBL11811550 | 0.75 | ADRB2 (0.30) | — | |
| SCHEMBL11806977 | 0.75 | HSD11B1 (0.34) | ABL1 | |
| SCHEMBL11517572 | 0.74 | KDM4E (0.40) | — | |
| SCHEMBL11819659 | 0.74 | — | — | |
| SCHEMBL11813005 | 0.73 | MAP3K12 (0.32) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |