Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 3/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517572 | 0.86 | KDM4E (0.40) | LMNATSHRKDM4ECDK9DYRK1A | |
| SCHEMBL11812486 | 0.82 | KMT2A (0.33) | CDK9DYRK1ADYRK2CSNK1ECLK1 | |
| SCHEMBL11805651 | 0.81 | CDK9 (0.40) | TSHRKDM4ECDK9DYRK1ADYRK2 | |
| SCHEMBL11809102 | 0.81 | CSNK1E (0.36) | DYRK1ADYRK2CSNK1ECLK1CLK2 | |
| SCHEMBL11804036 | 0.81 | TLR8 (0.38) | TSHRCDK9DYRK1ADYRK2HPGD | |
| SCHEMBL11811344 | 0.79 | DHFR (0.30) | — | |
| SCHEMBL11806977 | 0.79 | HSD11B1 (0.34) | LMNAKDM4ECDK9DYRK1AALDH1A1 | |
| SCHEMBL11804027 | 0.78 | DHFR (0.32) | — | |
| SCHEMBL11810331 | 0.78 | S1PR1 (0.34) | — | |
| SCHEMBL11812366 | 0.76 | ADRB2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |