Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRG | P23470 | 3/20 | 0.60 |
| ▸ | PTPRC | P08575 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | RHEB | Q15382 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817650 | 0.89 | PTPRG (0.76) | PTPRGPTPRCMEN1KMT2ARHEB | |
| SCHEMBL11818393 | 0.81 | KMT2A (0.60) | PTPRGPTPRCMEN1KMT2AHTT | |
| SCHEMBL11774987 | 0.81 | RAB9A (0.67) | PTPRGPTPRCMEN1KMT2AMETAP2 | |
| SCHEMBL11824913 | 0.79 | KMT2A (0.54) | PTPRGMEN1KMT2ARHEBHTT | |
| SCHEMBL11820343 | 0.77 | MRGPRX4 (0.54) | PTPRGPTPRCMEN1KMT2ARHEB | |
| SCHEMBL11818931 | 0.77 | FKBP1A (0.50) | PTPRGPTPRCMRGPRX4SORT1KDM4E | |
| SCHEMBL11814817 | 0.77 | PTPRG (0.48) | PTPRGPTPRCMEN1KMT2ARHEB | |
| SCHEMBL11822430 | 0.76 | ALDH1A1 (0.54) | PTPRGPTPRCMEN1KMT2AHTT | |
| SCHEMBL11817917 | 0.76 | PTPRG (0.47) | PTPRGPTPRCMEN1KMT2ARHEB | |
| SCHEMBL11812482 | 0.75 | MEN1 (0.51) | PTPRGPTPRCMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |