Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11822961 | 0.90 | ALDH1A1 (0.49) | ALDH1A1LMNATAS2R14SMN1; SMN2MEN1 | |
| SCHEMBL11853927 | 0.86 | TRPV4 (0.45) | ALDH1A1LMNAMEN1KMT2ARAB9A | |
| SCHEMBL11822899 | 0.85 | SMN1; SMN2 (0.44) | ALDH1A1LMNATAS2R14AKR1C3SMN1; SMN2 | |
| SCHEMBL11815261 | 0.83 | CNR2 (0.46) | ALDH1A1LMNATAS2R14SMN1; SMN2RAB9A | |
| SCHEMBL11823439 | 0.83 | AKR1C3 (0.46) | ALDH1A1TAS2R14AKR1C3SMN1; SMN2MEN1 | |
| SCHEMBL11820801 | 0.81 | NPC1 (0.45) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11822223 | 0.78 | MEN1 (0.46) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11819988 | 0.77 | LMNA (0.46) | ALDH1A1LMNATAS2R14AKR1C3MEN1 | |
| SCHEMBL11816930 | 0.77 | TAS2R14 (0.59) | TAS2R14MEN1KMT2APTGES | |
| SCHEMBL11815605 | 0.75 | CA12 (0.46) | ALDH1A1TAS2R14SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |