Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818108 | 0.88 | PTPRZ1 (0.40) | MRGPRX4MEP1BMEN1HPGDKMT2A | |
| SCHEMBL11820243 | 0.84 | MRGPRX4 (0.48) | MRGPRX4MEP1BKDM4EMEN1ALDH1A1 | |
| SCHEMBL11815385 | 0.83 | MRGPRX4 (0.46) | MRGPRX4MEP1BKDM4EMEN1ALDH1A1 | |
| SCHEMBL11825060 | 0.79 | MRGPRX4 (0.42) | MRGPRX4MEP1BKAT6AKDM4EMEN1 | |
| SCHEMBL11822411 | 0.79 | MRGPRX4 (0.40) | MRGPRX4MEP1BKAT6ABCHEACHE | |
| SCHEMBL11816465 | 0.79 | KDM5A (0.41) | MRGPRX4MEP1BKAT6ABCHEACHE | |
| SCHEMBL11823334 | 0.79 | MCL1 (0.44) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11826895 | 0.78 | PTPRC (0.46) | MRGPRX4MEN1HPGDKMT2APLA2G1B | |
| SCHEMBL11821945 | 0.78 | DAO (0.47) | MRGPRX4MEN1ALDH1A1KMT2APLA2G1B | |
| SCHEMBL24017232 | 0.74 | AURKA (0.44) | MRGPRX4MEP1BKAT6AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |