Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817074 | 0.87 | DAO (0.41) | MAPK1ALDH1A1HPGDMRGPRX4AURKA | |
| SCHEMBL11820243 | 0.85 | MRGPRX4 (0.48) | ALDH1A1HPGDMRGPRX4AURKATPX2 | |
| SCHEMBL11820625 | 0.81 | ALDH1A1 (0.47) | MAPK1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11820185 | 0.78 | AKR1C3 (0.43) | MAPK1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11817938 | 0.77 | TRPV1 (0.46) | TRPV1MAPK1ALDH1A1HPGDMRGPRX4 | |
| SCHEMBL11815385 | 0.77 | MRGPRX4 (0.46) | ALDH1A1HPGDMRGPRX4AURKATPX2 | |
| SCHEMBL11818108 | 0.74 | PTPRZ1 (0.40) | HPGDMRGPRX4AURKATPX2MEN1 | |
| SCHEMBL11818815 | 0.73 | MRGPRX4 (0.42) | ALDH1A1HPGDMRGPRX4AURKATPX2 | |
| SCHEMBL24017339 | 0.72 | KCNK2 (0.48) | MAPK1MRGPRX4AURKATPX2MEN1 | |
| SCHEMBL475754 | 0.71 | AURKA (0.56) | ALDH1A1MRGPRX4AURKATPX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |