Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | PTPRG | P23470 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824107 | 0.88 | CA2 (0.53) | KMT2AMEN1NPC1RAB9ATNF | |
| SCHEMBL11817200 | 0.88 | ALDH1A1 (0.53) | KMT2AMEN1NPC1RAB9ATNF | |
| SCHEMBL11817253 | 0.87 | PTPRG (0.52) | KMT2AMEN1NPC1RAB9ATNF | |
| SCHEMBL11819918 | 0.86 | KMT2A (0.47) | KMT2AMEN1RAB9ACA2CA4 | |
| SCHEMBL11825334 | 0.85 | KMT2A (0.43) | KMT2AMEN1CA2CA4PTPRG | |
| SCHEMBL11821805 | 0.85 | KMT2A (0.45) | KMT2AMEN1RAB9ACA2CA4 | |
| SCHEMBL11825369 | 0.85 | KMT2A (0.45) | KMT2AMEN1RAB9ACA2CA4 | |
| SCHEMBL11818393 | 0.82 | KMT2A (0.60) | KMT2AMEN1NPC1RAB9APTPRG | |
| SCHEMBL11818509 | 0.81 | POLB (0.45) | NPC1RAB9ATNFNOD1CA2 | |
| SCHEMBL11821552 | 0.81 | CA2 (0.42) | NPC1RAB9ATNFNOD1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |