Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 10/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | TPH1 | P17752 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821249 | 0.84 | ALDH1A1 (0.34) | PDE4APDE4DPDE4BPDE4CALDH1A1 | |
| SCHEMBL11816820 | 0.82 | KCNH2 (0.40) | PDE4APDE4DPDE4BPDE4CALDH1A1 | |
| SCHEMBL11820573 | 0.78 | ALDH1A1 (0.37) | PDE4APDE4DPDE4BPDE4CALDH1A1 | |
| SCHEMBL18287909 | 0.72 | MAOA (0.47) | PDE4APDE4DPDE4BPDE4CALDH1A1 | |
| SCHEMBL18287910 | 0.67 | MAOA (0.50) | PDE4APDE4BALDH1A1LMNAL3MBTL1 | |
| Benzene SCHEMBL11821265 | 0.65 | KDM4E (0.37) | PDE4APDE4DPDE4BPDE4CALDH1A1 | |
| SCHEMBL18844367 | 0.62 | ADRA1B (0.37) | PDE4DPDE4BALDH1A1LMNAMAPK1 | |
| SCHEMBL18535734 | 0.60 | MAOA (0.36) | PDE4APDE4DPDE4BPDE4CALDH1A1 | |
| SCHEMBL1659533 | 0.60 | PDE4A (0.48) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL27672272 | 0.59 | ALDH1A1 (0.51) | PDE4AALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941796-A | α-(Hydroxy and alkoxy substituted)phenyl-α-(2-piperidinyl)-methanols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-03-02 | — | — | US | disclosed |