Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816820 | 0.81 | KCNH2 (0.40) | ALDH1A1KDM4EL3MBTL1LMNAPDE4A | |
| SCHEMBL18287909 | 0.81 | MAOA (0.47) | ALDH1A1MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL11821249 | 0.80 | ALDH1A1 (0.34) | ALDH1A1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL11820552 | 0.78 | PDE4A (0.37) | ALDH1A1L3MBTL1MAPTHPGDLMNA | |
| SCHEMBL18287910 | 0.74 | MAOA (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| Benzene SCHEMBL11821265 | 0.71 | KDM4E (0.37) | ALDH1A1KDM4EKMT2AL3MBTL1LMNA | |
| SCHEMBL18535734 | 0.68 | MAOA (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL18844367 | 0.67 | ADRA1B (0.37) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL14722574 | 0.62 | CCR1 (0.40) | ALDH1A1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL13680448 | 0.62 | KDM4E (0.58) | ALDH1A1KDM4EMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941796-A | α-(Hydroxy and alkoxy substituted)phenyl-α-(2-piperidinyl)-methanols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-03-02 | — | — | US | disclosed |